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O 2 : superoxide anion radical

Assessment of glutathione/glutathione disulphide ratio and S -glutathionylated proteins in human blood, solid tissues, and cultured cells

Mechanistically, leptin up-regulates CBS expression through FOXO3a, promotes pre-TRH production by inhibiting the mTOR pathway, and then increases TH production and decreases corticosterone production, thus reducing fat deposition and improving insulin resistance induced by FHD (74)

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JAMA 314: 700707, 2015

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