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doi: 10.1186/s10194-021-01369-6, PMID: [DOI] [PMC free article] [PubMed] [Google Scholar] 206.Hammond NG, Colman I

Their clinical deployment is limited primarily by enrichment: CTCs occur at ultra-low frequencies and span heterogeneous phenotypic states, such that affinity-only capture often trades recovery for background contamination ( Electrospun nanofiber substrates offer a distinct advantage beyond ligand immobilization