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Like KIM-1, expression of CLU is significantly elevated in dedifferentiated tubular cells during AKI but also in polycystic kidney disease, nephrectomy, and renal cell carcinoma (Hidaka et al

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Adicionalmente, estimula la sntesis de colgeno tipo I y III y acta como un potente agente antioxidante, contribuyendo a la neutralizacin de especies reactivas de oxgeno en modelos experimentales

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