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Further investigations in case of negative abdominal ultrasound and strong clinical suspicion of gallbladder stones include endoscopic ultrasound or magnetic resonance imaging

K.KoH.LauL.YaoA.WongG.L.-H.et al (2023)

In individuals with PLPBP mutations, the most common metabolic abnormality is an increase in blood lactate and glucose levels, leading to metabolic acidosis shortly after birth, typically on day 1, then returns to normal by day 3 to 4 [11]

The BCSO-treated negative control group showed no mortality rate, and mice were very healthy and active, which indicates that BCSO is generally considered safe and has no adverse side effects []

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