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YE, yeast extract group rats received 3 g/kg ethanol+24.31 mg/kg of yeast extract (equal to the YE dose of 235.29 mg/60 kg human)

Similar events occur during inflammation and are exaggerated in cystic fibrosis patients

doi: 10.3390/genes10040260

In hereditary hemochromatosis, downregulation of the cystine-glutamate transporter directly exacerbates ferroptosis-driven liver injury, while N-acetylcysteine supplementation restores glutathione levels and inhibits ferroptotic cell death [54]
