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Es kann neuroprotektive Eigenschaften haben und wird mit der Verbesserung der kognitiven Funktion und mglicherweise der Verlangsamung des Fortschritts von neurodegenerativen Erkrankungen wie Alzheimer in Verbindung gebracht

however, Hejazi et al

Although most evidence remains correlative, the consistent findings across ethnically and geographically diverse cohorts underscore the clinical relevance of TMAO as a biomarker and potential therapeutic target in cardiovascular disease

In addition, TMAO induced several pro-atherogenic inflammatory proteins including cyclooxygenase 2, E-selectin, IL-6 and intracellular adhesion molecule 1 by activating NF-B (Seldin et al., 2016)

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All patients with a Divalproex sodium/valproate sodium exposed pregnancy and their partners should consider specialized prenatal monitoring to detect the possible occurrence of neural tube defects or other malformations