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The independent 2025 cell-line replication genuinely strengthens the specific claim that AEDG can influence telomere biology in human cells

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10.1186/s13046-016-0359-2 43 KlineC

3.1 In vitro models: from conventional to 3D spheroid and organoid models Like in other human tumors, traditional cultures of cell monolayer remain widely used in research, providing a controlled environment for rapid drug screening and genetic manipulation

[DOI] [PubMed] [Google Scholar] 103.Bradberry SM, Sheehan TMT, Barraclough CR, Vale JA

Sun D., Zou Y., Song L., et al., A Cyclodextrinbased Nanoformulation Achieves codelivery of Ginsenoside Rg3 and Quercetin for Chemoimmunotherapy in Colorectal Cancer, Acta Pharm Sin B 12, no
