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Tranexamic acid is the most promising of the three drugs to deliver whitening effects, but it also has the most potential for unwanted effects which include nausea, vomiting, palpitations and reduced menses in women

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These results underline the ability of GrimAge V2, PhenoAge, and OMICmAge in particular, to capture signals associated with key clinical biomarkers, and add to the growing body of literature on ketamines epigenetic mechanisms and their effect on biological aging

Cultured cells expressed markers typical of stellate cells

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We then examine several compounds capable of promoting NRF2 activity thereby inducing cytoprotective effects, and which are currently in different stages of clinical development for many pathologies, including neurodegenerative diseases