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If your deficiency is borderline and you're filling a smaller gap, the improvements are often more gradual and harder to pinpoint

Research Focus : Safety & Metabolism (Non-Clinical) Title : Safety and Metabolism of AOD9604, a Novel Nutraceutical Ingredient for Improved Metabolic Health (J Endocrinol Metab, Vol 4, No 3, June 2014) Authors : Margret I

Chapman LE, Darling AL, Brown JE (2015) The association between the biguanide drug metformin and vitamin B 12 deficiency in diabetic patients: a systematic review

This connection first came to our attention in 2018

"Folate and Vitamin B 12 Deficiency Exacerbate Inflammation during Mycobacterium avium paratuberculosis (MAP) Infection"

If you have allergies that could lead to anaphylaxis, a healthcare professional will likely recommend that you carry epinephrine with you at all times