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Abstract The intervertebral disc (IVD) is the fibrocartilaginous joint located between each vertebral body that confers flexibility and weight bearing capabilities to the spine

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It activates two receptor types simultaneously

doi: 10.3389/fcimb.2025.1603442 Received 02 April 2025 Accepted 21 July 2025 Published 11 August 2025 Volume 15 - 2025 Edited by Dinakaran Vasudevan, SKAN Research Trust, India Reviewed by Ieshita Pan, Saveetha University, India Zhaoxiang Wang, First Peoples Hospital of Kunshan, China Updates Copyright 2025 Tao, Yu, Tan, Huang, Huang, Lin and Yu