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As the next phase of this research, more sophisticated in vivo models, incorporating chronic injury paradigms, long-term follow-ups, and genetic or pharmacological modifications of inflammatory pathways, will be critical to substantiate the translational potential of this approach

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Major contributors to ROS production include mitochondrial dysfunction, cytochrome P450 2E1 (CYP2E1), and NADPH oxidase (NOX) enzymes

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Food and Drug Administration and are not intended to diagnose, treat, cure, or prevent any disease

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