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BMC Cancer 16 (1), 749

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In: Brigelius-Floh RSies H, (ed) Diversity of Selenium Functions in Health and Disease

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GH exerts autocrine/paracrine effects by binding to GHR in the same or a neighboring cell surface and initiating JAK2- and SRC-mediated signaling cascades, which decrease pro-apoptotic molecules (Bax and PPAR) and suppress caspase protein activation (Figure 4A)

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