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Faster kinetics and higher maximum fluorescence values are seen in DLB compared to PD 91,93

doi: 10.1097/CJI.0b013e3181ee6675 105 SiddiquiIErreniMVan BrakelMDebetsRAllavenaP

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Both doses were safe and well tolerated, but the high-dose regimen achieved markedly higher plasma concentrations and produced a faster, greater reduction in SOFA scores and inflammatory biomarkers (CRP and procalcitonin), while preventing thrombomodulin elevation (Fowler et al., 2014)