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Involvement of lactylation in physiology Lactate is an essential substance for various cellular physiological functions, playing a crucial regulatory role in energy metabolism, signal transduction, and maintaining microenvironment homeostasis

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[DOI] [PMC free article] [PubMed] [Google Scholar] 155.Fazeli PK, Horowitz MC, MacDougald OA, Scheller EL, Rodeheffer MS, Rosen CJ, Klibanski A
FDA and EMA approval processes require a risk-benefit assessment that requires consideration of many complex factors (e.g., therapeutic context, seriousness of condition)
