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Blood samples were immediately collected form the vena cava

Besides increased enterohepatic reabsorption of bilirubin, decreased hepatic uptake, and conjugation, are the major factors contributing to the impaired elimination of bilirubin observed after birth (Kaplan et al., The rationale for the use of metalloporphyrins The bilirubin production rate of newborn infants is normally two to three times higher than that of adults, which is mainly due to an increased circulating RBC mass and a shortened RBC lifespan, and hence an increase in RBC turnover (Stevenson et al., 1994)

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four studies, 369 participants)

10.1046/J.1472-765X.2003.01351.X

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