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The study included all patients with any type of melasma

1) was confirmed by 1 H NMR: 1.7 ( 1 H, ddd, J =13.9, 7.0, 5.3 Hz), 2.12.5 [ 4 H, 2.15 (ddd, J =13.7, 8.1, 7.5 Hz), 2.45 (ddtd, J =9.5, 7.6, 7.4, 6.8 Hz), 2.41 (ddd, J =13.9, 9.4, 7.6 Hz), 2.21 (ddd, J =13.7, 6.8, 4.1 Hz)], 3.64.0 [ 2 H, 3.72 (td, J =9.4, 5.3 Hz), 4.01 (d, J =7.4 Hz)], 4.4 ( 1 H, dddd, J =8.1, 7.6, 7.0, 4.1 Hz), 7.55 ( 1 H, s)

Brain Res 742(1-2):8088 Wang W, Liu L, Chen C, Jiang P, Zhang T (2018) Protective effects of dopamine D2/D3 receptor agonist piribedil on learning and memory of rats exposed to global cerebral ischemiareperfusion

Glutathione is an antioxidant that reduces the formation of free radicals, thereby reducing the early signs of aging, such as wrinkles, age spots, and lines, making the skin youthful

Gastroenterology 137 , 466481 (2009)

Both stimulate collagen production, but through fundamentally different mechanisms and understanding these differences is key to selecting the right compound for specific research objectives