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Acknowledgements The author is grateful to the National Institutes of Health (R35GM142882) for support which enables investigations into halogenation biochemistry in the Agarwal laboratory

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Semaglutide (Wegovy) for the treatment of obesity or weight management should not be used during pregnancy because weight loss offers no potential benefit to a pregnant woman and may result in fetal harm due to the potential hazard of maternal weight loss to the fetus

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The chondroitin sulfate proteoglycans neurocan and phosphacan are expressed by reactive astrocytes in the chronic CNS glial scar

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Severe or concerning symptoms warrant medical attention and discontinuation of use

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