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When glutamate was injected into the ganglia innervating the temporalis or masseter muscle, there was a significant increase in nociception (decrease in afferent mechanical thresholds) that was attenuated by NMDAR antagonists (2R)-amino-5-phosphonovaleric acid, AP-V) or worsened by EAAT blockers (3S)-3-[[3-[[4-(Trifluoromethyl)benzoyl]amino]phenyl]methoxy]-L-aspartic acid, TFB- TBOA) [267]

Notably, TNBC have been shown to more sensitive to ferroptosis than estrogen receptor (ER) positive breast cancer, suggesting that ferroptosis is a promising treatment for TNBC patients

Bu durumun belirtileri genellikle halsizlik, enfeksiyonlara kar dirensizlik ve oksidatif stresle ilikili hastalklarn (rnein, kronik yorgunluk, otoimmn hastalklar) ortaya kmas eklinde kendini gsterir

1995;269:E551-E556 121

This has prompted the exploration of novel molecular strategies, including the use of peptides as therapeutic agents 49 - 53