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Key points The -cells of the pancreatic islets secrete somatostatin, a powerful paracrine inhibitor of both insulin and glucagon secretion from islet -cells and -cells

According to the CDC, excessive alcohol intake leads to an economic cost of $249 billion per year 15 , with most of the cost (72%) resulting from decreased productivity in the workplace, and 11% of the cost dedicated to health care expenses related to excessive drinking 16

[7] See also [edit] References [edit] Annual Review of Biochemistry

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