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Its considered experimental, and its safety and efficacy profiles have not been firmly established through large-scale clinical trials

Values for the scoring functions of Epitalon indicating strong binding, represented by the ICM-Score, were acquired (Table 4)

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GSTs, primarily GSTA1-1, are involved in the first step of the metabolic pathway of busulfan 79,80

Common side effects may include: Dizziness Pain, swelling, or itching at the injection site Diarrhea Nausea Skin rash or acne-like skin Unwell or feeling of weakness Serious side effects may include: Difficulty breathing Swelling of the face, lips, or tongue Irregular heartbeats or palpitations Swelling or pain in the limbs due to blood clots Severe dizziness or weakness This list does not cover all potential side effects, and others may occur

Moreover, recent research sheds light on MOTS-c's role beyond mitochondrial function, revealing its ability to translocate to the nucleus in response to metabolic stress