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34,35 Obesity

1b) 7,13,14,15
Novel propargyl-linked bisubstrate analogues as tight-binding inhibitors for nicotinamide N -methyltransferase

CuellarSantoyo et al
At concentrations lower than those of DON, JHU395 has been found to decrease the growth and increase the apoptosis of high-MYC medulloblastoma cell lines, thereby prolonging the survival of treated animals (100)

2,2,2-(((2,4,6-trimethylbenzene-1,3,5-triyl)tris(methylene))tris(1H-1,2,3-triazole-1,4-diyl))tris(benzo[d]thiazole) (TC-Benzo): To a stirring solution of triazide (119 mg, 0.4 mmol) in methanol (20 mL), were added solutions of CuSO4 (5 mol%) and (+)-Sodium L-ascorbate (20 mol %) in water (0.5 ml each)