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In addition to promoting tumor proliferation, circRNAs interact with the TME to increase GBM progression
GPXs can catalyze the reduction of hydrogen peroxide or organic hydroperoxides to water or corresponding alcohols with the help of GSH [146]

doi: 10.1186/ar1784 207 DerryHMFagundesCPAndridgeRGlaserRMalarkeyWBKiecolt-GlaserJK

Nevertheless, more studies are needed to elucidate the inflammatory activity of LDX

The reactive oxygen species (or the oxidative damage it causes) should always be demonstrable at the site of injury
It exists both as a membrane-bound or soluble molecule
