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For example, an animal study performed with postnatal piglets was performed to observe Lf's effect on neurodevelopment (Chen et al., For the potential use of Lf for PD treatment, a mouse model has been used (Xu et al., 2019)

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Cystinosin-LKG, the alternatively spliced isoform of cystinosin, has a broader localization that could be leveraged to reduce cystine accumulation, restore lysosomal function, and lower apoptosis rates in cystinotic proximal tubule cells [155]

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is supported by an NHMRC Postgraduate Scholarship and the Australian and New Zealand Association of Neurologists Gwen James Dementia Fellowship

Statements Author contributions SY, JA, and NC conceptualized the content of the manuscript