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[DOI] [PubMed] [Google Scholar] Castelli MC, Wong D, Friedman K, Bhargava P, Riley GM

In a rat model of intervertebral disc degeneration, MOTS-c injection preserved disc height (82.4% versus 58.7% in the untreated group), restored MRI signals indicating improved disc hydration, and reduced histological degeneration scores by 44% compared to untreated controls

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As a derivative of methylquinolinium (MQ), 5-amino-1-methylquinolinium exhibits excellent cell membrane permeability and biocompatibility
