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However, it differs from other forms of PCD in that ferroptosis is based on divalent iron and leads to cell death by promoting lethal accumulation of intracellular lipid peroxides [12]

Total endogenous antioxidant levels and malignancy grades in brain tumors have also been found to be inversely correlated

Structural basis of arrestin-dependent signal transduction

However, the reasons and mechanisms for its upregulation in BC require further study (Wang et al., 2020)

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Br J Urol 1992