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McCormick Z

This insight can then guide the development of multifaceted strategies targeting immune organs, cells, and signaling pathways to restore immune competence, eliminate SnCs, and delay age-related dysfunction

After GSH is utilized, the oxidizing environment facilitates the reoxidation of protein thiols by interacting with protein disulfide isomerase (PDI) and endoplasmic reticulum oxidoreduction (ERO-1) (Higa and Chevet, 2012)