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Synthetic mRNAs, which transiently express functional cystinosin, have demonstrated beneficial and sustained impacts on proximal tubular resorptive function, proteinuria, and kidney morphology in zebrafish after treatment [157]

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Almost all carnitine (99%) is intracellular [5]

Cardiovascular disease may be triggered by gut microbiota, microbial metabolites, gut wall reactions, and inflammation

Targeting intensive versus conventional glycaemic control for type 1 diabetes mellitus: a systematic review with meta-analyses and trial sequential analyses of randomised clinical trials
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Reducing TMAO levels may mitigate inflammation, oxidative stress, endothelial dysfunction, and renal abnormalities, and improving patient outcomes
