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Current research hotspots involve developing derivatives with improved pharmacokinetic properties based on these lead compounds, or utilizing advanced drug delivery systems like nanoparticles, hydrogenated coconut oil microspheres, and degradable hydrogels to enhance their targeted delivery efficiency and therapeutic index (Table 1)

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Lactate dehydrogenase (LDH) LDH regenerates NAD + consumed in the GAPDH reaction, producing lactate, the end-product of anaerobic glycolysis Two molecules of pyruvate have exactly the same number of carbons and oxygens as one molecule of glucose

[DOI] [PubMed] [Google Scholar] 64.Miralles L.M

additional symptoms include inflammation of the tongue, sores or ulcers of the mouth, and ulcers of the skin at the corners of the mouth (12)