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In addition, they exhibited increased cell clustering, apoptosis, MMP expression, and collagen denaturation compared to control discs
Its not FDA-approved, and selling it as a drug or supplement in the US isnt legal (source)
This of course depends on the drug preparation method and its half-life
These bidirectional modulatory effects suggest interaction with aminergic tone regulation rather than direct receptor agonism
Since IC is a chronic condition, therapy and monitoring should be carried out over the long term [19]
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