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BA-induced LRO autofluorescence and gene expression require daf-16 , hsf-1 , and pmk-1 BA exposure was shown to activate two cytosolic stress regulators, the DAF-16 and SKN-1 transcription factors, which, along with the pmk-1 p38 MAP kinase ortholog were all required to survive BA toxicity 26

Eventually, they become so short that the cell cant divide anymore and becomes inactive or dies

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HTS by NMR of Combinatorial Libraries: A Fragment-based Approach To Ligand Discovery

Investigation, A.B