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The damaging effects of Nrf2 modification in the lung, as an example, may increase the susceptibility of the affected tissues to the oxidative stress of the oxygen environment, as well as compromise the function of epithelial cells and phagocytes, such as granulocytic leukocytes and monocytes/macrophages [49,50]
The population used in establishing this data may be important, for example age or study size may skew or misrepresent interpretation (Santonen et al
Gilbertson RJ, Graham TA
S.KarasuM.PrasadB
Individual absorption : Factors like age and digestive health can affect B12 absorption
A meta-analysis of proinflammatory cytokines in chronic heart failure
