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To overcome the limitations of first-generation inhibitors, next-generation autophagy inhibitors such as Lys05 and DQ661 have been developed
Though these techniques have been proven effective, their brain-targeting efficiency and safety need further improvement
Conjugated BAs, including taurocholic acid (TCA), taurochenodeoxycholic acid (TCDCA), and tauroursodeoxycholic acid (TUDCA), inhibit IL-6 expression in macrophage lines (38)
