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Description
In the past, mortality rates reached 80% of cases and were mostly determined by the progression of cerebral edema and multiple system organ failure [1,2]

This high energy demand creates a byproduct of oxidative stress
Exposure to pathogens trains the immune system, which enhances the future immune response

[13] (cf

This contrasts markedly with full-length growth hormone, which can impair glucose tolerance and potentially precipitate or worsen diabetes

10.1016/j.neuron.2005.05.010 86 MasliahE.RockensteinE.ManteM.CrewsL.SpencerB.AdameA.et al
