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Since then mechanistic studies, animal models and human feeding studies have confirmed that ingestion of L-carnitine, choline and similar compounds raises urinary and breath levels of TMA and TMAO in many people

This "metabolic buffering" role helps maintain the CoA/acyl-CoA ratio essential for TCA cycle function [1]

doi: 10.1515/CCLM.2005.069 13 MarcocciCKahalyGJKrassasGEBartalenaLPrummelMStahlMet al

L-carnitine can also help people with heart disease and patients who have had a minor heart attack

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[6] Specifically, in this study conducted by Patrick Jacobs and colleagues, 24 healthy, exercise trained men consumed either 4.5 grams of GPLC or a placebo on two different days separated by one week (double blind, cross-over study design)