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Disruption of oxidative homeostasis in the cardiovascular system can lead to oxidative stress, causing cellular damage and cardiovascular disease (38)

doi: 10.1016/j.mrfmmm.2003.09.001 16 GriveauJFLannouDL
However, numerous studies document higher incidences of mitochondrial abnormalities in affected individuals

Front Cell Dev Biol 9:116
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