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73,74 Tumor suppressor BRCA1-associated protein 1 (BAP1) frequently mutated or deleted in sporadic human cancers, inactivation of BAP1 inhibited ferroptosis by releasing SLC7A11 inhibition, thus BAP1 mutated cancer cells were sensitive to SLC7A11 inhibitor erastin
When diagnosed in middle age, diabetes reduces life expectancy by roughly 10 years, and worldwide one person dies every nine seconds from diabetes-related causes (IDF 2025
The most common adverse event with SS-31 is injection site reaction
For context, each unit marking on an insulin syringe represents 0.01ml
The developed NPs here were highly efficient when compared to free drug administration, so they have a high potential for clinical translation and future nanotheranostics applications, especially in CRC targeting nanoplatforms ( Pirouzmand et al
Additionally, refractory M
