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Massa et al., 2017) and with Platelet Activating Factor Receptor (PAFr) (Jen et al., 2013), as demonstrated in endothelial cells and upper airway epithelial cells, respectively

These enzymes produce a large panel of alcohols, diols, triols, ketones and epoxides, as well as metabolites possessing a combination of these moieties

Notably, the expression of -6-fatty acid desaturase 2 (FAD2) is upregulated, enhancing unsaturated fatty acid synthesis, while lysophosphatidylcholine acyltransferase is downregulated, leading to increased level of polyunsaturated fatty acid (PUFA) (Mapelli-Brahm et al