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RAS is an upstream activator of the MAP-kinase pathway, and consistent with this, Spitz nevus has high levels of phosphorylated ERK, which is a component in this pathway [121]

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7(2): 259 Mancini I, Bruera E

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Interleukin-6 (IL6) a Pleiotropic Cytokine

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The most problematic is extreme expansion, with the structure swelling by up to 300% when fully charged

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Trends Biochem Sci 2007

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