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B12 Deficiency: If there is a vitamin B12 deficiency, the starting dosage of 30mcg is administered beneath the skin or into the muscle daily for scheduled days to boost the overall levels

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Several RNAi drugs, including aptamers like pegaptanib targeting protein targets, and micro interfering RNAs like givosiran and patisiran, as well as antisense oligonucleotides like golodirsen and inotersen that interfere directly with RNA targets, have received FDA approval for medical use (Yu et al., 2020)

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