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Recent studies have reported that hyperandrogenemia induces disorders of glucose and lipid metabolism at the central and peripheral levels, promoting the development and progression of obesity and type 2 diabetes in both female individuals and rodents with PCOS (40, 41)

Changes in brain membrane phospholipid and high-energy phosphate metabolism precede dementia Neurobiol Aging 1995

Effects of lipid-lowering pharmaceutical clofibrate on lipid and lipoprotein metabolism of grass carp ( Ctenopharyngodon idella Val.) fed with the high non-protein energy diets

cJUN N-terminal kinase (JNK) activation mediates islet amyloid-induced beta cell apoptosis in cultured human islet amyloid polypeptide transgenic mouse islets Diabetologia 55 1: 166-74

The phenolic composition of EVOO determines its strong antioxidant activity and is responsible for the pleiotropic positive effects of its consumption, ranging from metabolic and cardiovascular risk reduction to the improvement of chronic inflammation [134, 135]