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Letter by Violi and Pignatelli regarding article, "Effects of random allocation to vitamin E supplementation on the occurrence of venous thromboembolism: report from the Women's Health Study"

Among these inhibitors, one mixed-type inhibitor from hydroxypyridinone-l-phenylalanine conjugates named ((S)-(5-(benzyloxy)-1-octyl-4-oxo-1,4-dihydropyridin-2-yl) methyl 2-amino-3-phenylpropanoate) showed potent inhibitory effect with IC 50 values of 12.6 and 4.0 M for monophenolase and diphenolase activities, respectively 362