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The novel -aspartyl transferase activity of PsGGT was applied for the synthesis of L--aspartyl hydroxamate (BAH) using 80 mM L-asparagine (donor substrate) and 40 mM hydroxylammonium chloride (acceptor substrate) with 0.106 mM product yield (Prihanto et al., 2015b)

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For control, MRAB-3 biofilms were treated with 1 PBS

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Henceforth, these two compensating mechanisms can induce the expression of serine synthesis genes, including PHGDH (57) (Supplementary Figure 1)

Employing this rat model of HMG-induced lung injury, we observed significant attenuation of the pulmonary injury when experimental animals were complement or neutrophil depleted prior to HMG challenge