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Akt, activated by insulin signaling, phosphorylates PGC-1 at serine-570, leading to inhibition of its activity [47]

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[DOI] [PubMed] [Google Scholar] 46.Holme E., Jodal U., Linstedt S., Nordin I

Linked to the electromechanical alterations induced by LCAC exposure is an array of effects on cardiac excitation-contraction coupling mechanisms that overload the cardiomyocyte cytosol with Na + and Ca 2+ ions
