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We then built the isobologram of the corresponding dose-response curves with a fixed dose ratio of R and compared the expected mixture of the two doses that produced an effect equal to half of the maximal effect produced by the individual drugs and to the experimental value (see later in methods)

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This plant has been used since the past as an anti-inflammatory agent for the treatment of inflammatory diseases in Korea ( S ,7 S )- O -(2-methyl butanol)-columbianetin reduced histamine and tryptase levels