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Have a BMI of 27 or higher with at least one medical condition linked to obesity, such as high blood pressure, diabetes, or sleep apnea

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[DOI] [PubMed] [Google Scholar] 58.Drucker DJ, Erlich P, Asa SL, Brubaker PL

With NO bioavailability maintained, endothelium-mediated vasorelaxation was preserved and vascular remodeling and fibrosis were prevented (Helmstadter et al

Doses vary depending on the individual

For example, the effect of retatrutide on gastric emptying varies with concentration, which could affect the absorption of oral medications taken at different times relative to injection