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J Neurodev Disord 3:132143

Poor IL-12 production correlated with a deficiency in intracellular reduced glutathione (GSH) concentrations in diabetic patients

others (like celastrol, a large triterpene) might not cross readily but can influence the CNS indirectly via peripheral immune modulation [110]

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Its produced primarily in the liver forming the enzyme glutathione peroxidise and is important for many aspects of cellular function