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Description
M., Fuller C

5-Amino-1MQ is a first-in-class small molecule inhibitor designed to target Nicotinamide N-methyltransferase (NNMT), a cytosolic enzyme that acts as a master regulator of the cellular "metabolic drain."

J.et al (2016)

In the Neelakantan study, diet-induced obese (DIO) C57BL/6 mice were treated with NNMT inhibitors including 5-Amino-1MQ analogues
Evolving incretin-based therapies in Japan: optimizing treatment strategies for diverse clinical and socioeconomical profiles in type 2 diabetes

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