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The amount of copper in most copper peptide serums is low enough that it shouldnt pose a major risk to most healthy people, but its still something to be mindful of.15 However, those with Wilsons disease a rare genetic condition may be best off avoiding copper peptide serums (or any skin care product containing copper), as the condition causes the element to build up in the body.16 Cancer risks GHK-Cu seemingly promotes angiogenesis, or the formation of new blood vessels.14 Though this can lead to beneficial outcomes like better wound healing, it may also lead to the growth or spread of cancer by giving solid tumors a blood supply.17 This means that if you have active or suspected cancer, it may be wise to avoid copper peptides

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Early studies carried out with cell-free extracts of Neurospora crassa demonstrated the requirement of three amino acids (viz., Cys, l-histidine (His), and l-methionine (Met)) for ERG biosynthesis 11,12

Arch Toxicol 86, 345391

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Both are widely known for their antioxidant properties, skin-brightening benefits, and role in boosting immunity