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15 This supports prior studies, which concluded that treatment for 10 days was as effective as longer treatment regimens

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In rare cases, thiamine hypersensitivity, including urticaria, anaphylactoid reactions, collapse, and death have occurred, primarily following repeated parenteral administration

With advancements in microbiome research, gut microbiota have been identified as pivotal regulators of host metabolism and immunity, modulating host redox homeostasis through metabolite secretion, epithelial barrier repair, and immunomodulation [6,7,8]

Ward et al., 2024)