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Vitamin B12-Depot-Injektopas 1500 g is a vitamin preparation

In another aspect of the invention, one or more NNMT inhibitors (such as a cation of Formula I or IA, or otherwise disclosed herein) is contacted with a cell expressing NNMT followed by contacting said cell expressing NNMT with one or more chemical entities (e.g., nicotinamide riboside, nicotinamide mononucleotide) that increase intracellular NAD+ levels to provide muscular therapy

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With adjustments to lifestyle and temporary or oral B12 supplementation, B12 levels can be increased and made stable